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Ixazomib is a novel, once-weekly, oral proteasome inhibitor with activity against both ixazomib-sensitive and -resistant multiple myeloma cells. Analysis of the cost effectiveness of ixazomib in refractory and relapsed multiple myeloma (RRMM) compared with bortezomib. A Markov decision analytic model was used to simulate the long-term cost effectiveness of ixazomib vs. bortezomib in RRMM from the US healthcare payer perspective. A 10-year time horizon and lifetime costs and health outcomes were assessed. Patients received bortezomib or ixazomib based on a dose-dense approach. Costs, quality-adjusted life years (QALYs) and incremental cost-effectiveness ratios (ICERs) were derived using published data on treatment regimen-related adverse events, clinical efficacy, and costs. Sensitivity analyses were performed. The model simulated 778 RRMM patients in each arm. The mean estimated total direct costs over 10 years were US$89,018 (ixazomib) and US$80,269 (bortezomib), with ICERs of $48,700 and $59,051 per QALY gained in the ixazomib and bortezomib arms, respectively. Sensitivity analyses of the base-case results showed the cost-effectiveness of
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Problem installing glib
I want to use numarray. I installed numarray using pip so I have the same files on my python installation as I installed from:
Can’t I just be certain that I have all the glib packages installed as well using:
or just copying the contents of the directories?
A:
You have three ways to get numarray from python:
(pip install numarray)
(setup.py install)
(pip (or pip2) install numarray )
So it depends which you installed, but if you don’t know, try to see if python says you installed it.
ACI
The ACI (Aeronautic Combat Information Center) is a combat management computer built by Honeywell in the 1960s as part of the Aeronautical Combat Information Center (ACIC). Initially known as the ACIC, it was first used as the primary cockpit display system for the F-4, and became standard on many USAF fighter aircraft. Modern ACI systems are still used with the F-16, F/A-18, F-15, and F-5.
History
The AC